1.医用金属表面活性涂层构建及其体内体外生物学性能评价；

2.金属表面耐蚀耐磨涂层的构建及其评价。

科研与学术工作经历：

1. 2014/1 - 至今，太阳成集团tyc234cc，材料科学与工程，副教授

2. 2010/1 - 2013/12，太阳成集团tyc234cc，材料科学与工程，讲师

教育经历：

1.2006/9 - 2009/12，太阳成集团tyc234cc，材料学，博士

2.2004/9 - 2006/6，武汉理工大学，材料学，硕士

3.2000/9 - 2004/6，武汉理工大学，材料学，学士

1. 国家自然科学基金面上项目，51771142，磁性羟基磷灰石纳米管涂层设计及其肽控释抗菌与骨整合, 2018/01-2021/12,60 万元，在研，主持

2. 国家自然科学基金面上项目,51571158, 多孔钛孔壁纳米纤维化结构设计及其皮下软组织整合机制与抗菌性能, 2016/01-2019/12,62 万元，在研，主持

3. 国家重点研发计划（参与单位），2016YFC1100604，3D 打印个性化植入器械表面钙磷硅涂层的制备和表征，2016/07-2020/12,44.24万元，在研，主持

4. 国家自然科学青年基金项目,51201129，TiO2纳米管/钛界面强化机制及其渐变管径的肽控释抗菌行为，2013/01-2015/12，25万元，已结题，主持

5.陕西省自然科学基金青年项目，2015JQ5130，钛表面纳米纤维结构设计及其软组织相关细胞的响应效应与抗菌性能， 2016/01-201,7/12，3万元，已结题，主持

6.国家教育部博士点基金（新教工基金），20110201120001， 基于人体硬组织修复应用的氧化锆仿骨基质结构设计与关键技术研究 ，2012/01-2014/12，4万元，已结题，主持

第一作者论文：

[1]         Lan Zhang Juan Zhang, Yong Han. Cytocompatibility and antibacterial activity of nanostructured H₂Ti₅O₁₁•H₂O outlayered Zn-doped TiO₂ coatings on Ti for application in percutaneous implants. Scientific Reports 2017,7:13951

[2]         Lan Zhang, Jiaqi Guo, Ting Yan, Yong Han. Fibroblast responses and antibacterial activity of Cu and Zn co-doped TiO₂ for percutaneous implants. Applied Surface Science 2018, 434: 633  

[3]         Lan Zhang, Xiaoyan Huang, Yong Han. Formation mechanism and cytocompatibility of nano-shaped calcium silicate hydrate/calcium titanium silicate/TiO₂ composite coatings on titanium, Journal of Materials Chemistry B 2016,4:6734 

[4]         Lan Zhang, Jiaqi Guo, Xiaoyan Huang, Yanni Zhang, Yong Han. Dual function of Cu-doped TiO₂ coatings on titanium for the application of percutaneous implants, Journal of Materials Chemistry B 2016,4:3788.  

[5]         Lan Zhang, Wenting Zhang, Yong Han. A nanoplate-like a-Al₂O₃ out-layered Al₂O₃-ZrO₂ coating fabricated by micro-arc oxidation for hip joint prosthesis, Applied surface science 2016,61: 141.

[6]         Lan Zhang,Qin Gao, Yong Han. Zn and Ag Co-doped Anti-microbial TiO₂ Coatings on Ti by Micro-arc Oxidation, Journal of Materials Science & Technology 2016, 32: 919. 

[7]         Lan Zhang, Yong Han. Hydroxyaptite nanorods patterned ZrO₂ bilayer coating on zirconium for the application of percutaneous implants, Colloids and Surfaces B: Biointerfaces 2015,127:8 

[8]         Lan Zhang, Yong Han. Formation and bioactivity of HA nanorods on micro-arc oxidized zirconium, Materials Science and Engineering C 2014,43:86 

[9]         Lan Zhang, Yong Han. Interfacial structure and enhanced adhesion between anodized ZrO₂ nanotube films and Zr substrates by sedimentation of fluoride ions, Surface & Coatings Technology, 2012,212:192-198. 

[10]      Lan Zhang, Yong Han. Enhanced anodization growth of self-organized ZrO₂ nanotubes on nanostructured zirconium, Surface & Coatings Technology, 2011,205:2876-2881.  

[11]      Lan Zhang, Yong Han. Enhanced bioactivity of self-organized ZrO₂ nanotube layer by annealing and UV irradiation, Materials Science and Engineering C 2011, 31: 1104- 1110. 

[12]      Lan Zhang, Yong Han. Ultraviolet-enhanced wettability and bioactivity of self-organized TiO₂ nanotube layer, Journal of Nanoscience and Nanotechnology, 2011,12:10908-12 .

[13]      Lan Zhang，Yong Han. Effect of nanostructured titanium on anodization growth of self-organized TiO₂ nanotubes, Nanotechnology, 2010, 21:055602  

[14]      Lan Zhang，Yong Han. Twins formation and their role in nanostructuring of zirconium, Materials Science and Engineering A, 2009,523:130-133  

[15]      Lan Zhang，Yong Han. Nanocrystallization of zirconium subjected to surface mechanical attrition treatment, Nanotechnology, 2008, 19:165706  

授权专利：

【1】张兰,憨勇,王少波，一种改善ZrO₂纳米管结合强度的氟离子沉降阳极氧化方法,2014.6.4，中国，ZL201110445736.6

【2】张兰,黄小燕, 憨勇,一种纳米纤维、带状硅酸钙/二氧化钛生物活性涂层的制备方法，2016.12.05，中国，ZL2014122900613260